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How Hydroquinone cream is used as a bleaching agent to lighten dark skin tones such as age spots, melasma, acne marks, and freckles.
How Hydroquinone Creams Work
Hydroquinone works by increasing the breakdown of the melanin pigment granules called melanosomes in the skin's melanocytes, or pigment cells. It does so by inhibiting tyrosinase activity, the enzyme required to produce melanin.
Is Hydroquinone Effective?
For most people, the effects of using hydroquinone can be noticed after about a month of treatment - sometimes longer. If there is no visible change after using hydroquinone after 3 months, it's recommended to stop using it. Not everyone will benefit from using hydroquinone.
However, in order to enhance the effects of hydroquinone, it's best to stay out of the sun, use a sunscreen with at least SPF15 if you are in the sun, and wear protective clothing as well. Never use a tanning bed or sunlamp of any kind when using hydroquinone cream.
In order to reach the desired amount of skin bleaching, it is important to continue to use hydroquinone on a regular basis as directed. Once you see the results you want, use only as necessary to maintain the desired effects.
How to Effectively Use Hydroquinone Cream
- First, give your skin a sensitivity test prior to applying the cream. If no itching or redness occurs in less than 24 hours, it's safe to begin the treatment
- Thoroughly clean and dry your skin prior to applying a thin layer of hydroquinone cream twice a day to the skin areas you want to lighten. Rub the cream into your skin well.
- Only use enough to cover the targeted areas and refrain from touching your regular skin or it will lighten is as well. Afterwards, quickly wash your hands. Do not touch anything until you have completely washed your hands.
- Avoid applying the cream near the mouth, eyes, and other sensitive mucous membranes.
- While using hydroquinone, do not use any other topical product, especially peroxide, unless your doctor directs you to do so.
- If you use non-medicated cosmetics, moisturizing lotions, or sunscreens, always apply the hydroquinone cream first. Wait a number of minutes before applying the others.
Side Effects of Hydroquinone
Hydroquinone cream is tolerated very well. Just be aware that some women may experience temporary skin irritations as well as minor itching, and sometimes a bit of skin reddening. These conditions will likely pass rather quickly and should not be a problem. However, if the problem persists, stop applying the cream.
In rare cases, some people have experienced severe burning, swelling, crusting, and itching. This side effect could possibly stem from an allergic reaction and you should seek medical attention immediately.
Extensive use of hydroquinone has been linked to a chronic blue-black pigmentation known as exogenous ochronosis. This is quite rare, and for the most part has only occurred in Africa. Likely reasons for this condition stem from other ingredients such as antimalarial agents, resorcinol, and phenol, which have all been linked in triggering ochronosis.




